White matter hyperintensities affect transcranial electrical stimulation in the aging brain
نویسندگان
چکیده
منابع مشابه
White matter hyperintensities and normal-appearing white matter integrity in the aging brain
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline. It is unknown how WMH form, although white matter degeneration is characterized pathologically by demyelination, axonal loss, and rarefaction, often attributed to ischemia. Changes within normal-appearin...
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Transcranial current stimulation (TCS) is a neuromodulation method in which the patient is exposed to a mild electric current (direct or alternating) at 1-2 mA, resulting in an increase or a decrease in the brain excitability. This modi.cation in neural activities can be used as a method for functional human brain mapping with causal inferences. This method might also facilitate the treatments ...
متن کاملWhite matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain.
BACKGROUND AND PURPOSE Aging is accompanied by clinically silent cerebral white matter injury identified through white matter hyperintensities (WMHs) on fluid-attenuated inversion recovery (FLAIR)- and diffusion tensor imaging-based measures of white matter integrity. The temporal course of FLAIR and diffusion tensor imaging changes within WMHs and their less-injured periphery (ie, their penumb...
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OBJECTIVE To evaluate the brain status of patients with systemic sclerosis (SSc). METHODS Fourteen female patients with SSc aged 24-74, with a disease duration of 1-12 years and without other relevant systemic diseases, were enrolled. All patients and an age matched female control group (CG) of 14 clinically normal subjects, underwent brain magnetic resonance examination at 1.5 T; spin echo p...
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Case-control studies showed that migraine is associated with ischemic stroke. Studies assessing the prevalence of white matter lesions (WML) in migraine however, reported conflicting results, possibly attributable to selection bias by recruiting only severe cases. We conducted a population-based MRI study of migraineurs with aura (N=161), migraineurs without aura (N=134) and controls (N=140), 3...
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ژورنال
عنوان ژورنال: Brain Stimulation
سال: 2021
ISSN: 1935-861X
DOI: 10.1016/j.brs.2020.11.009